As in any large city, there has always been a thriving nightclub culture in Manchester, but its place in the history of modern clubbing surpasses that of every other city in the UK with the possible exception of London.

UK broadcaster Jimmy Savile is credited as becoming the first modern DJ by using twin turntables for continuous play after he obtained two domestic record decks welded together. He first used this device to play to the public in 1946, at a nightclub called The Ritz on Whitworth Street (which had opened in 1927). Tony Prince is credited as becoming the world’s first full-time club DJ in 1964 when Savile, who was then a Mecca manager in Manchester, told him that Top Rank considered him to be the first person to be on their payroll as a pure DJ.

Many teenagers of the 1960s developed a love for Northern Soul, which had as two of its epicentres the Wigan Casino and Manchester’s Twisted Wheel Club, and is credited as being instrumental in the development of the Motown Sound.

Rob Gretton, members of New Order (the band formed from the remaining members of Joy Division after singer Ian Curtis’ suicide) and Factory Records boss Tony Wilson opened Fac 51 The Hacienda on Whitworth Street in 1982. It quickly became the focus of electronic music and the start of house music, the Madchester sound, and the Ibiza scene, which all came together in the Summer of Love in 1988. The Hacienda was also at the setting of the 2002 movie 24 Hour Party People.

Other historical clubs and nights in Manchester include
“Naked under leather” - one of the UK birthplaces of Electronic Music.
“The Number One” - the first gay rave/house club.
“Bowlers” - home of happy hardcore.
“Paradise Factory” and “The Breakfast Club” at Manto.
“Home”.
“Flesh”.
“Homoelectric”.
“Danceteria”.

One of the oldest and most diverse venues is the Band on the Wall, a live music venue in the Northern Quarter area of the city. This venue was built around 1862 as the flagship pub of a local brewery; it was originally called The George and Dragon. It got its nickname in the late 1920s or early 1930s from the stage high on the back wall. In 1975 it was taken on by jazz musician Steve Morris and his business partner Frank Cusick, and renamed The Band on the Wal.